Substitutes for R22

For futher information and alternatives see Refrigerant Report A-501-20.

Substitutes (safety group A1) for CFC and HCFC refrigerants (status as of 09.2018)

Former
Refrigerants

Substitutes (safety group A1)*

ASHRAE
Classification

Trade Name

Composition
(with blends)

Detailed
Information

R12
(R500)

R134a

-

R134a as substitute for R12 and R22

R22/R502

R404A

various

R143a/125/
134a

R404A and R507A as substitutes for R22 and R502

R507A

various

R143a/125

R422A

ISCEON® MO79

Chemours

R143a/125/
600a

R422A as substitute for R22 and R502

R22

R407A

Mexichem,
Arkema

R32/125/134a

R407A/B/F/H as substitutes for R22 and R502

R407C

various

R32/125/134a

R407C as substitute for R22

R407F

Genetron® Performax LT

Honeywell

R32/125/134a

R407A/B/F/H as substitutes for R22 and R502

R407H

-

Daikin Chemical

R32/125/134a

R407A/B/F/H as substitutes for R22 and R502

R417A

ISCEON® MO59

Chemours

R125/134a/600

R417A/417B/422D/438A as substitutes for R22

R417B➀

-

Daikin Chemical

R125/134a/600

R422D➀

ISCEON® MO29

Chemours

R125/134a/600a

R427A

Forane® 427A

Arkema

R32/125/143a/
134a

R427A as a substitute for R22

R438A

ISCEON® MO99

Chemours

R32/125/134a/
600/601a

R417A/417B/422D/438A as substitutes for R22

* For further information see Refrigerant data and Application ranges in the Refrigerant Report.

➀ Prohibited in countries of the EU from 2020 on.