HFC refrigerants

Substitutes for CFC and HCFC refrigerants (chlorine free HFCs) (status as of 09.2020)
①: flammable
②: service refrigerant with ODP = 0

Former
Refrigerants

Alternatives

ASHRAE
Classification

Trade Name

Composition
(with blends)

Detailed
Information

R12
(R500)

R134a

-

-

R134a as substitute for R12 and R22

R152a①

-

-

R152a – an alternative to R134a (?)

R437A②

ISCEON® MO49 Plus

Chemours

R125/134a/600/
601

Service blends as substitutes for R12 (R500)

R22/R502

R404A

various

R143a/125/
134a

R404A and R507A as substitutes for R22 and R502

R507A

various

R143a/125

R422A

ISCEON® MO79

Chemours

R143a/125/
600a

R422A as substitute for R22 and R502

R22

R407A

-

Koura (Mexichem),
Arkema

R32/125/134a

R407A/B/F/H as substitutes for R22 and R502

R407C

various

R32/125/134a

R407C as substitute for R22

R407F

Genetron® Performax LT

Honeywell

R32/125/134a

R407A/B/F/H as substitutes for R22 and R502

R407H

-

Daikin Chemical

R32/125/134a

R407A/B/F/H as substitutes for R22 and R502

R410A

various

R32/125

R410A as substitute for R22

R417A

ISCEON® MO59

Chemours

R125/134a/600

R417A/417B/422D/438A as substitutes for R22

R417B

-

Daikin Chemical

R125/134a/600

R422D

ISCEON® MO29

Chemours

R125/134a/600a

R427A

Forane® 427A

Arkema

R32/125/143a/
134a

R427A as a substitute for R22

R438A

ISCEON® MO99

Chemours

R32/125/134a/
600/601a

R417A/417B/422D/438A as substitutes for R22

R114

R12B1

R236fa

-

-

Alternatives for R114 and R12B1

R227ea

-

-

R13B1

R410A

various

R32/125

Alternatives for R13B1

R13

R503

R23

-

-

Alternatives for R13 and R503

R508A

KLEA® 508A

Koura (Mexichem)

R23/116

R508B

Suva® 95

Chemours

R23/116